Pirfenidone Tablet (Pirfenex)

a. FDA-Approved Uses

Pirfenidone is an antifibrotic compound primarily authorized to manage Idiopathic Pulmonary Fibrosis (IPF)1. It provides a pathway for treating the disease, and extensive clinical studies have shown its effectiveness in slowing down the decline of lung function2. Here are some references to support this information:

• The effects and safety of pirfenidone in the treatment of idiopathic pulmonary fibrosis2
• Pirfenidone improves survival in IPF: results from a real-world experience1

b. Off-Label Uses

Pirfenidone is an antifibrotic compound primarily authorized to manage Idiopathic Pulmonary Fibrosis (IPF)1. It provides a pathway for treating the disease and extensive clinical studies have shown its effectiveness in slowing down the decline of lung function2.

a. Common Side Effects

The side effects commonly reported are nausea, fatigue, and loss of appetite.

b. Serious Side Effects

Liver toxicity is an uncommon occurrence, but there have been some reports of hepatic failure. Additionally, photosensitivity is a side effect that, while not as frequent, still holds importance.

c. Long-Term Side Effects

We should establish monitoring measures to minimize any potential long-term consequences.